Radiation brings out leukemia Depend on dosage and position

Radiation brings out leukemia Depend on dosage and position
After receiving the nuclear radiation of certain dosage, will cause the leukemia morbidity to rise. The investigation shows, after Japan Hiroshima and the intersection of Nagasaki and atomic bomb explode 1945, receive serious leukemia of resident, area of radiation, morbidity to receive the intersection of radiation and 30 times and 17 times of district respectively. And this time the situation of nuclear incident of leakage of Japan is more serious, certainly will cause the relative increase of the leukemia morbidity.
The so-called radiation is a kind of energy that the radioactive material launches out in the form of wave or particle, it is mainly three kinds of rays of ,��,��. Its harmfulness is mainly absorbed through breathing sucking, skin wound and digestive tract, entered body, or is absorbed in certain distance by the human body, lead to the fact various diseases take place.
Leukemia is the malignant illness of the blood system, it is a malignant cloning disease of a group of heterogeneity, systematic malignant tumour of hematopoiesis that it is hematopoietic stem cell or grandfather's cell sudden change caused. Its characteristic is unusual leucocyte and inmature cell ' Namely leukaemia cell) The going on, unusual hyperplasia out of control in bone marrow or other hematopoiesis are organized, soak various tissues, make normal cells produce and reduce.
The leukemia one clinical manifestation in order to generating heat, anaemia, bleeding, liver spleen lymph node characteristics greatly swollen, including acute leukemia and chronic leukemia. The precise reason of leukemia is not so obvious at present, but a large amount of scientific research shows, radioactive rays, some chemicals, virus and inherent cause,etc. can bring out leukemia. Among them nuclear radiation may bring out leukemia, its function and radiating the dosage big or small and relevant to shining in the position. One time heavy dose of shining while being low dose of, can cause leukemia is chromosome and abnormal state of gene mainly many times, emergence which cause leukemia. If size 15 chromosome and the malposition of the chromosome can lead to the fact acute young grains of cell leukemia early the 17th, the existence of Ph chromosome causes chronic grains of cellulous leukemia,etc..
Leukemia that radiation causes is the same as leukemia symptom that other reasons cause, mainly shown as generating heat, anaemia and bleeding,etc.. No matter leukemia that any reasons cause, in case of not getting appropriate treatment in time, if is acute leukemia, will die within half a year generally.
Acute leukemia (AL) Therapeutic method although more,it is antitumor chemistry treat still as most effective treatment. The chemistry treatment of AL made progress greatly in the seventies of the 20th century, there is no survival rate of disease at children's acute lymphocyte leukemia (ALL) in 3~5 China is up to more than 70%, adult ALL is up to 35%; Children's acute marrow leukemia (AML) It is 40%~50%, and the adult AML is about 30%. The purpose of chemotherapy lies in eliminating the leukaemia cells as many as possible or controlling a large amount of hyperplasia of its, by removing various clinical manifestation that are caused by that the leukaemia cell is soaked, and offer the advantage for recovery of the normal hematopoietic function.
Generally there is a bad reaction of inhibiting the hematopoietic function in the daily chemotherapy medicine at present, and toxicant to the liver, kidney, gastrointestinal tract. So should observe the condition, following up a case by regular visits to the blood in the chemotherapy course closely and is like, liver renal function closely, adjust dosage and chemotherapy scheme at any time. Should kill the leukaemia cell in a large amount, as well as protect the normal cell group as much as possible. Chemotherapy scheme and necessary individual of dosage, fix on the basis of progress and the patient's objective condition of the type of leukemia, course of disease. Must strengthen various support treatments in chemotherapy while, in order to prevent bleeding and infecting, guarantee the harmony of chemotherapy.
The healing solution of the acute leukemia is concrete as follows:
Generally support to treat: Prevent being infected with, corrected anaemia, control and bled, prevented and cured high urine acidaemia, maintained nutrition.
The chemotherapy of antineoplastic: It follow early, union, capacity, stage by stage ( Induce and relieve, consolidate and strengthen, keep treating) Principle. There are three kinds of daily chemotherapy schemes. AML: The classical standard induces the scheme as DA scheme ' Candy afterbirth glucoside of gentle erythromycin + A) . ALL: No matter the intersection of children and ALL or standard, ALL of adult, induce, relieve the scheme for VDLP ' Changchun alkali + gentle erythromycin + the intersection of door and winter the intersection of amide and enzyme + splash loose Buddhist nun) . The hematopoietic stem cell transplants: Expect to be cured through bone-marrow transplantation.
Except young grains of cell leukemia and children non- high to endanger ALL for a long time, conditional to have suitable to support the body, should all carry on different genetic bone marrow transplant or one's own bone-marrow transplantation early, especially difficult managing AL or estimates and recurs the dangerous patient greatly after chemotherapy.
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